Composition and method for treatment of wounds

Details Composition and method for treatment of wounds Composition and method for treatment of wounds

A - Human Necessities

61

K

A61K 38/17 (2006.01) A61K 38/48 (2006.01) A61L 15/38 (2006.01) A61P 17/02 (2006.01) C07K 14/435 (2006.01) C07K 14/705 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2467246

A composition for treatment of a wound to promote healing thereof in a human or non-human mammal comprises an active amount of a toll receptor (or toll- like receptor) ligand, or a precursor thereof, and a suitable carrier. The ligand may be a spatzle or spatzle-like protein derived from an insect, such as Drosophila melanogaster or Lucilia sericata. The invention also relates to a method of treating a wound which comprises applying to the wound a composition according to the invention, and a dressing for a wound which comprises a support carrying composition according to the invention.

L'invention concerne une composition pour le traitement d'une plaie, destinée à stimuler la guérison de cette plaie chez un mammifère humain ou non humain. Cette composition comprend une quantité active d'un ligand d'un récepteur Toll (ou d'un récepteur du type Toll), ou d'un précurseur de celui-ci, et un transporteur approprié. Ce ligand peut être une protéine Spatzle ou de type Spatzle dérivée d'un insecte tel que Drosophila melanogaster ou Lucilia sericata. L'invention concerne également un procédé permettant de traiter une plaie, lequel consiste à appliquer sur la plaie une composition produite selon cette invention, ainsi qu'un bandage pour une plaie comprenant un support transportant une composition produite selon cette invention.

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