The use of bile acid derivatives

A - Human Necessities – 61 – K

Patent

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A61K 49/00 (2006.01)

Patent

CA 2229530

The invention relates to the use of a coloured or fluorescent hepatobiliary targeting compound in the manufacture of an administrable composition for visualising the bile duct and biliary leakage during an operation in the region of the bile duct, and is useful as an aid to a surgeon performing an operation in the region of the gall bladder. The compound is preferably based on a steroid moiety.

L'invention concerne l'utilisation d'un composé de ciblage hépatobiliaire coloré ou fluorescent, dans la fabrication d'une composition administrée pour visualiser le canal cholédoque et les fuites biliaires au cours d'une opération dans la région du canal cholédoque. En outre, cette composition permet d'aider le chirurgien lors d'une opération dans la région de la vésicule biliaire. Le composé est, de préférence, à base d'un fragment stéroïde.

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