Thymic stromal lymphopoietin promoter and uses therefor

Details Thymic stromal lymphopoietin promoter and uses therefor Thymic stromal lymphopoietin promoter and uses therefor

C - Chemistry, Metallurgy

07

H

C07H 21/04 (2006.01) A01K 67/027 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2575721

A promoter comprising the isolated promoter region of the human Thymic Stromal Lymphopoietin (TSLP) gene and functional portions of the promoter region having TSLP promoter activity. The promoters are useful for identifying promoter agonists and antagonists that can be used to prevent or treat allergic conditions and autoimmune diseases.

L'invention concerne un promoteur comprenant la région isolée de promoteurs du gène de lymphopoïétine stromale humaine (TSLP) et des parties fonctionnelles de la région de promoteurs possédant une activité de promoteurs de TSLP humaine. Les promoteurs sont utiles pour identifier les agonistes des promoteurs et les antagonistes qui peuvent s'utiliser pour prévenir ou traiter des états allergiques et des maladies auto-immunes.

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