A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/095 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2722765
In various aspects of the present invention, nanoparticle compositions are provided which comprise (a) nanoparticles comprising at least one biodegradable polymer and (b) at least one pharmaceutical associated with the nanoparticles. In other aspects of the present invention, methods of forming nanoparticles compositions are provided, which comprise contacting a first liquid that comprises one or more biodegradable polymers dissolved in a first solvent with a second liquid that comprises a second solvent which is miscible with the first solvent while being a non-solvent for the one or more biodegradable polymers, such that nanoparticles are formed.
La présente invention concerne, dans divers aspects, des compositions de nanoparticules qui comprennent (a) des nanoparticules comportant au moins un polymère biodégradable et (b) au moins un produit pharmaceutique associé auxdites nanoparticules. Dans dautres aspects, la présente invention concerne des procédés de formation de compositions de nanoparticules qui comprennent la mise en contact dun premier liquide comportant un ou plusieurs polymères biodégradables dissous dans un premier solvant avec un second liquide comportant un second solvant; ledit second solvant est miscible avec le premier solvant tout en étant non-solvant pour le ou les polymères biodégradables, de telle sorte que des nanoparticules se forment.
Chakrapani Aravind
O'hagan Derek T.
Singh Manmohan
Borden Ladner Gervais Llp
Novartis Ag
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