Methods and compositions for deterring abuse of orally...

A - Human Necessities – 61 – K

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A61K 47/30 (2006.01) A61K 47/06 (2006.01) A61K 31/485 (2006.01)

Patent

CA 2647360

This invention relates to an abuse deterrent formulation of an oral dosage form of a therapeutically effective amount of any active drug substance that can be subject to abuse combined with a gel forming polymer, a nasal mucosal irritating surfactant and a flushing agent. Such a dosage form is intended to deter abuse of the active drug substance via injection, nasal inhalation or consumption of quantities of the dosage unit exceeding the usual therapeutically effective dose.

Formulation de dissuasion d'abus comprenant une forme pharmaceutique orale de quantité thérapeutiquement efficace de médicament actif quelconque pouvant faire l'objet d'abus, en combinaison avec un polymère formant gel, un tensioactif d'irritation mucorales nasale et un agent de lavage. Cette forme pharmaceutique vise à dissuader l'abus de médicament actif par injection, inhalation nasale ou consommation de quantités de l'unité posologique excédant la dose habituelle thérapeutiquement efficace.

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