A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 1/28 (2006.01) A61K 47/18 (2006.01) A61K 47/22 (2006.01) A61K 47/26 (2006.01) A61K 47/36 (2006.01) A61K 47/42 (2006.01) A61P 39/06 (2006.01)
Patent
CA 2626680
Peritoneal dialysis solutions are specially formulated for use during and immediately after an episode of peritonitis. The solutions include one or more additives to minimize the injury and physiological effects that peritonitis can cause. One additive is a mixture of amino acids sufficient to maintain a positive nitrogen balance, at least one of the amino acids being present in a di-peptide form. Another additive is a compound that scavenges free radicals generated by peritoneal macrophages activated by the peritonitis. Another additive is chondroitin sulfate that changes the permeability of the peritoneal membrane during subsequent dialysis using solutions free of chondroitin sulfate. Another additive is the degradation products of hyaluronic acid to enhance the regeneration of the pritoneal mesothelium without fibrosis.
Breborowicz Andrzej
Oreopoulos Dimitrios G.
Baxter International Inc.
Sim & Mcburney
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