Composition for the treatment of damaged tissue

A - Human Necessities – 61 – K

Patent

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Details

A61K 45/06 (2006.01) A61K 38/18 (2006.01) A61K 38/48 (2006.01) A61K 38/49 (2006.01) A61K 38/55 (2006.01) A61P 17/02 (2006.01)

Patent

CA 2395487

A pharmaceutical for use in damaged tissue, such as wound, treatment (e.g. healing) is described. The pharmaceutical comprising a composition which comprises: (a) a growth factor; and (b) an inhibitor agent; and optionally (c) a pharmaceutically acceptable carrier, diluent or excipient; wherein the inhibitor agent can inhibit the action of at least one specific adverse protein (e.g. a specific protease) that is upregulated in a damaged tissue, such as a wound, environment.

La présente invention concerne un produit pharmaceutique convenant au traitement, et notamment à la guérison d'un tissu lésé tel que dans le cas d'une blessure. Ce produit pharmaceutique est constitué d'une composition comprenant (a) un facteur de croissance, (b) un inhibiteur, et éventuellement (c) un vecteur, diluant ou excipient pharmaceutiquement acceptable. En l'occurrence, l'inhibiteur est capable de bloquer l'action d'au moins une protéine contre-productive, notamment d'une protéase spécifique, dont la production augmente dans un environnement de tissu lésé, comme dans le cas d'une blessure.

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