Amplified cancer gene wip1

Details Amplified cancer gene wip1 Amplified cancer gene wip1

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2438420

There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the WIP1 gene, which are amplified breast, and/or lung, and/or colon, and/or ovarian, and/or prostate cancer genes. The WIP1 gene, its expressed protein products and antibodies are used diagnostically or as targets for cancer therapy; they are also used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.

L'invention concerne des méthodes et des compositions pour le diagnostic, la prévention et le traitement de tumeurs et de cancers chez des mammifères, notamment des êtres humains. Ces méthodes et ces compositions utilisent les gènes WIP1, qui sont des gènes amplifiés du cancer du sein et/ou du poumon et/ou du côlon et/ou des ovaires et/ou de la prostate. Le gène WIP1, ses produits protéiniques et ses anticorps exprimés sont utilisés à des fins diagnostiques ou en tant que cibles pour la thérapie du cancer ainsi que pour l'identification de composés et de réactifs utiles pour le diagnostic, la prévention et la thérapie du cancer.

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