Method for treating leukemias

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07H 21/02 (2006.01) C07K 14/82 (2006.01) C12N 15/11 (2006.01) C12N 15/12 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2086105

2086105 9200080 PCTABS00010 A novel ribozyme, capable of selectively cleaving the bcr-abl mRNA of a cell containing the Philadelphia Chromosome, thereby blocking synthesis of BCR-ABL protein is provided. Methods for using the ribozyme for treating leukemia patients and methods of producing the ribozymes are also provided.

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