Psca: prostate stem cell antigen

Details Psca: prostate stem cell antigen Psca: prostate stem cell antigen

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2281877

The invention provides a novel prostate-specific cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors.

La présente invention concerne un nouvel antigène prostatique spécifique de surface, baptisé antigène de cellule souche prostatique (PSCA), largement surexprimé à tous les stades du cancer de la prostate, y compris dans les néoplasies prostatiques intraépithéliales de haut grade, et dans les tumeurs de la prostate liées aux androgènes et non liées aux androgènes.

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