Interleukin-10 antibodies

Details Interleukin-10 antibodies Interleukin-10 antibodies

C - Chemistry, Metallurgy

07

K

C07K 16/24 (2006.01) C07K 16/46 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2545255

The methods and compositions provided herein relate generally to IL-10 specific antibodies and uses thereof. More specifically, compositions of humanized IL-10 specific antibodies and methods to use such antibodies in modulating the biological activity of IL-10, particularly in autoimmune disorders and pathogen-mediated immunopathology.

La présente invention concerne des méthodes et des compositions généralement associées à des anticorps dirigés spécifiquement contre IL-10 et l'utilisation desdits anticorps. Plus spécifiquement, elle concerne des compositions d'anticorps humanisés spécifiquement dirigés contre IL-10 et des méthodes d'utilisation de ces anticorps pour moduler l'activité biologique de IL-10, en particulier dans des maladies auto-immunes et dans l'immunopathologie médiée par des pathogènes.

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