Compounds for oral dosage of active substances requiring a...

A - Human Necessities – 61 – K

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Details

A61K 47/14 (2006.01) A61K 9/16 (2006.01) A61K 47/44 (2006.01) A61J 3/00 (2006.01)

Patent

CA 2510373

The invention relates to a compound for oral dosage of active substances having a bitter taste which comprises from 15 to 30 % of an active substance mixed with 60 to 80 % of glycerol ester or fat acid, eventually added with wax, and added with a surface active agent and is produced by a spray-cooling method making it possible to obtain granulometry of less than 350 µm.

Composition destinée à l~administration orale de principes actifs de goût inacceptable, caractérisée en ce qu~elle comprend de 15 à 30% de principe actif mélangé à 60 à 80% d~un ester de glycérol ou d~un acide gras, éventuellement additionné d~une cire, et additionné d~un agent tensio-actif et en ce qu~elles sont préparées par un procédé de spray-cooling pouvant conduire à une granulométrie à 350 ~m.

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