A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/517 (2006.01) A61K 31/00 (2006.01) A61K 38/57 (2006.01) C07D 239/94 (2006.01)
Patent
CA 2392554
The present invention describes a therapeutic method useful for treating or preventing a condition of platelet aggregation in a subject including administering a pharmaceutically effective amount of a compound or composition that inhibits JAK-3 and/or tyrosine phosphorylation of STAT-3 and inhibits thrombin induced platelet aggregation. The condition of platelet aggregation includes hematopoietic and cerebrovascular diseases.
La présente invention concerne une technique thérapeutique destinée au traitement ou à la prévention d'une agrégation de plaquettes chez un sujet, qui consiste à administrer une quantité pharmaceutiquement efficace d'un composé ou d'une composition, laquelle inhibe JAK-3 et/ou la phosphorylation tyrosine de STAT-3 et inhibe ainsi l'agrégation de plaquettes. Parmi les pathologies liées à cette agrégation de plaquette figurent les maladies hématopoïétiques et cérébro-vasculaires.
Goudreau Gage Dubuc
Parker Hughes Institute
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