Process for preparing amorphous salts

C - Chemistry – Metallurgy – 07 – D

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C07D 403/02 (2006.01)

Patent

CA 2600456

Amorphous solid omeprazole magnesium or esomeprazole magnesium is prepared by subjecting a solution of omeprazole magnesium or esomeprazole magnesium to flash evaporation, such as by using an agitated thin film drier-vertical.

Du magnésium d'oméprazole ou d'ésoméprazole solide amorphe est préparé par soumission d'une solution de magnésium d'oméprazole ou d'ésoméprazole à l'évaporation éclair, par exemple en utilisant un séchoir vertical à film mince agité.

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