C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/12 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/53 (2006.01) C07D 253/07 (2006.01) C07D 257/04 (2006.01) C07D 271/06 (2006.01) C07D 277/24 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01) C07D 521/00 (2006.01)
Patent
CA 2188806
Compounds of formula (I) wherein: Azo is alkylte- trazolyl or is chosen. from the group consisting of oxa- diazolyl, imidazolyl, pyrazolyl, triazolyl, oxazolyl, tri- azinyl, thiazolyl, isothiazolyl or any of these substituted; Y is an alkylene bridge of 3-9 carbon atoms; R1 and R2 are each individually chosen from hydrogen, halo alkyl, alkenyl, amino, alkylthio, hydroxy, hydroxyalkyl alkoxyalkyl, alkylthioalkyl, alkylsulfinylalkyl, alkylsul- fonylalkyl, alkoxy, nitro, carboxy, alkoxycarbonyl, dialky- laminoalkyl, alkylaminoalkyl, aminoalkyl, difluoromethyl, trifluoromethyl or cyano; R3 is alkoxycarbonyl, alkyltetra- zolyl, phenyl or a heterocycle chosen from benzoxazolyl, benzathiazolyl, thiadiazolyl, imidazolyl, dihydroimidazolyl, oxazolyl thiazolyl oxadiazolyl, pyrazolyl, isoxazolyl, isothiazolyl, furyl, triazolyl, tetrazolyl, thiophenyl, pyridyl, pyrimidinyl, pyrazinyl, pyridinyl or substi- tuted phenyl or subsdtited heterocyclyl are an effective antipicornaviral agents.
Aldous David J.
Bailey Thomas R.
Diana Guy Dominic
Kuo Gee-Hong
Nitz Theodore J.
Fetherstonhaugh & Co.
Sanofi-Synthelabo
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