Aqueous suspension of loteprednol etabonate

Details Aqueous suspension of loteprednol etabonate Aqueous suspension of loteprednol etabonate

A - Human Necessities

61

K

A61K 31/565 (2006.01) A61K 9/00 (2006.01) A61K 9/10 (2006.01) A61K 31/56 (2006.01) A61K 47/18 (2006.01)

Patent

CA 2231977

The conventional aqueous suspension of loteprednol etabonate is not easily amenable to production pH control and entails a pH depression on long-term storage, thus irritating the eye or the nasal mucosa on instillation. When a C2-7 aliphatic amino acid is added to an aqueous suspension of loteprednol etabonate for topical ophthalmic use, the suspension does not undergo pH depression even on prolonged storage, with the result that no irritable response is elicited in the eye or nasal mucosa.

La suspension classique d'étabonate de loteprednol ne se prête pas facilement au contrôle du pH, qui baisse lors de la conservation à long terme, ce qui a comme effet d'irriter par instillation les yeux et la muqueuse nasale. Lorsqu'un acide aliphatique aminé C2-7 est ajouté à la suspension aqueuse d'étabonate de loteprednol aux fins d'applications en ophtalmologie, la suspension ne subit pas une baisse de pH même lors d'une conservation prolongée, ce qui élimine l'action irritante au niveau des yeux et de la muqueuse nasale.

Affiliated with

Also associated with

Rating

Aqueous suspension of loteprednol etabonate does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aqueous suspension of loteprednol etabonate, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aqueous suspension of loteprednol etabonate will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1754170