Use of group i mglur antagonists in the treatment of fragile...

A - Human Necessities – 61 – K

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A61K 45/08 (2006.01) A61K 31/00 (2006.01) A61K 31/198 (2006.01) A61K 31/44 (2006.01) A61K 31/472 (2006.01) A61K 31/4725 (2006.01) A61P 25/00 (2006.01) A61P 25/18 (2006.01) A61P 25/28 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2442478

Compositions and uses of mGluR5 antagonists for the treatment and prevention of neurological disorders, such as Fragile X, autism, mental retardation, schizophrenia and Down's Syndrome, are disclosed.

L'invention concerne des compositions et les utilisations d'antagonistes de mGluR5 pour le traitement et la prévention de troubles neurologiques tels que le syndrome du X fragile, l'autisme, l'arriération mentale, la schizophrénie, et la trisomie 21.

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