New use of artemin, a member of the gdnf ligand family

A - Human Necessities – 61 – K

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Details

A61K 38/18 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2432977

The present invention concerns the use of artemin for the prevention or treatment of nerve cell injury and changes associated with nerve cell injury. More particularly the present invention provides for a method of protecting neurons in a mammal from injury-induced pathological changes and a method of treating neuronal damage in a mammal by administering artemin or an artemin agonist.

La présente invention concerne l'utilisation de l'artémine pour la prévention ou le traitement de lésions des cellules nerveuses et des modifications associées à de telles lésions. Plus particulièrement, cette invention concerne une méthode permettant de protéger les neurones chez un mammifère contre des modifications pathologiques induites par une lésion ainsi qu'une méthode de traitement des dégâts neuronaux chez un mammifère par administration d'artémine ou d'un agoniste d'artémine.

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