Anionic furanose derivatives, methods of making and using...

C - Chemistry – Metallurgy – 07 – H

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C07H 11/00 (2006.01) A61K 31/70 (2006.01) C07H 9/04 (2006.01) C07H 13/00 (2006.01) C07H 13/04 (2006.01) C07H 15/04 (2006.01) C07H 15/18 (2006.01)

Patent

CA 2088669

2088669 9202525 PCTABS00010 A glucofuranose derivative substituted at the 3,5,6- or 3,6-positions with a radical that provides an anionic charge at physiological pH values is disclosed, as are pharmaceutical compositions, and methods of making and using the same. The compounds are useful in treating inflammation, and particularly conditions that involve neutrophil influx; they are also useful in inhibiting gastric ulcer formation.

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