Localized delivery of drug combinations

Details Localized delivery of drug combinations Localized delivery of drug combinations

A - Human Necessities

61

M

A61M 31/00 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2630538

Implants comprising controlled delivery matrices, associated with, or including medical devices, having stably and releasably associated therewith predetermined non- antagonistic combinations of two or more therapeutic agents provide control of the ratio of these agents at a localized site. Methods of identifying such combinations are also disclosed.

La présente invention a trait à des implants comportant des matrices d'administration contrôlée, associées à, ou comportant des dispositifs médicaux, ayant en association stable et libérable des combinaisons non antagonistes prédéterminés d'au moins deux agents thérapeutiques assurant le contrôle du rapport de ces agents au niveau d'un site localisé. L'invention a également trait à des procédés d'identification de telles combinaisons.

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