Dithiane and dithiolane nitrato derivatives

Details Dithiane and dithiolane nitrato derivatives Dithiane and dithiolane nitrato derivatives

C - Chemistry, Metallurgy

07

D

C07D 339/04 (2006.01) A61K 31/385 (2006.01) C07D 339/08 (2006.01)

Patent

CA 2284620

An organic compound is provided which contains at least one nitric oxide donor group and at least one group being, or being adapted to be converted in vivo to a free sulfhydryl group. A preferred compound contains at least one sulfhydryl group, either in the reduced -SH form or in the oxidized -S-S- disulfide form.

La présente invention concerne un composé organique contenant au moins un groupe donneur oxyde nitrique et au moins un groupe qui est transformé ou qui est apte à se transformer in vivo en un groupe sulfhydryle libre. Un composé préféré contient au moins un groupe sulfhydryle, sous la forme réduite -SH ou sous la forme oxydée -S-S-disulfure.

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