Monotherapy for the treatment of amyotrophic lateral...

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A61K 31/635 (2006.01) A61K 31/00 (2006.01) A61K 31/10 (2006.01) A61K 31/16 (2006.01) A61K 31/18 (2006.01) A61K 31/196 (2006.01) A61K 31/352 (2006.01) A61K 31/365 (2006.01) A61K 31/382 (2006.01) A61K 31/415 (2006.01) A61K 31/421 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/437 (2006.01) A61K 31/4418 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) A61K 31/47 (2006.01) A61K 31/4745 (2006.01) A61K 31/50 (2006.01) A61K 31/501 (2006.01) A61K 31/519 (2006.01) A61K 31/535 (2006.01) A61K 31/5

Patent

CA 2487923

A method of treating, preventing, or inhibiting ALS, in a subject in need of such treatment, inhibition or prevention. The method comprises administering to a subject one or more cyclooxygenase-2 selective inhibitor(s), or isomer(s), or pharmaceutically acceptable salt(s), ester(s), or prodrug(s) thereof, wherein the amount of the cyclooxygenase-2 selective inhibitor(s), isomer(s), ester(s), salt(s) or prodrug(s) thereof constitutes an ALS treatment, inhibition or prevention effective amount of the COX 2 inhibitor(s).

L'invention concerne une méthode permettant de traiter, prévenir ou inhiber la sclérose amyotrophique latérale (ALS) chez un sujet ayant besoin de traitement, de prévention ou d'inhibition. Ladite méthode consiste à administrer à un sujet un ou plusieurs inhibiteur(s) sélectif(s) de la cyclooxygénase-2, un ou des isomère(s), un ou des sels pharmaceutiquement acceptables, un ou des ester(s) ou un ou des promédicament(s) de ceux-ci. La quantité d'inhibiteurs sélectifs de la cyclooxygénase-2, d'isomère(s), d'ester(s), de sel(s) ou de promédicament(s) de ceux-ci constitue une quantité efficace pour traiter, prévenir ou inhiber l'ALS

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