A - Human Necessities – 01 – K
Patent
A - Human Necessities
01
K
A01K 67/027 (2006.01) C12N 5/06 (2006.01)
Patent
CA 2530210
The present invention provides non-inbred mouse embryonic stem (ES) cells comprising alleles derived from at least two different mouse strains and having high developmental potential. The ES cells optionally comprises a docking site for a transgene. Methods for production of the ES cells are also disclosed. This invention further provides chimeric and transgenic mice derived from the non-inbred ES cells and methods for deriving such mice.
La présente invention a trait à des cellules souches embryonnaires de souris non consanguines comportant des allèles dérivés d'au moins deux souches de souris différentes et présentant un potentiel élevé de développement. Les cellules souches embryonnaires comportent un site d'attache pour un transgène. L'invention a également trait à des procédés pour la production des cellules souches embryonnaires. L'invention a trait en outre à des souris chimériques et transgéniques dérivées des cellules souches embryonnaires non consanguines et des procédés pour obtenir de telles souris.
Osler Hoskin & Harcourt Llp
University Mcgill
LandOfFree
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