Methods and apparatus for rapid crystallization of biomolecules

Details Methods and apparatus for rapid crystallization of biomolecules Methods and apparatus for rapid crystallization of biomolecules

C - Chemistry, Metallurgy

30

B

C30B 29/54 (2006.01) C07K 1/00 (2006.01) G01N 1/10 (2006.01)

Patent

CA 2537636

The present invention relates to methods and apparatus for promoting rapid formation of biomolecule crystals from a solution of biomolecules, preferably proteins, wherein the protein solution undergoes rapid concentration according to its isoelectric point in an electric field. Protein crystallization according to the methods of the present invention takes place within a period of hours or less.

La présente invention concerne des procédés et des dispositifs pour favoriser la formation rapide de cristaux de molécules biologiques à partir d'une solution de molécules biologiques, de préférence des protéines, la solution de protéines subissant une concentration rapide en fonction de son point isoélectrique dans un champ magnétique. La cristallisation des protéines selon les procédés de l'invention, se déroule pendant un intervalle de temps de plusieurs heures ou moins.

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