Acid soluble proteins from micellar casein

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/47 (2006.01) A23J 3/32 (2006.01) A23J 3/34 (2006.01) A23L 1/305 (2006.01) A61K 35/20 (2006.01) A61K 38/17 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2538507

The present invention relates to a milk fraction obtainable by acidification of micellar casein and separation from precipitated casein named acid soluble protein from micellar casein. It was found that the milk fraction and especially certain sub-fractions thereof are bioactive and promote GLP-1 release in vitro. Based on these results, acid soluble protein from micellar casein may be useful in the treatment and the prevention of diabetes type II, obesity and may further be added to formulas directed at other purposes addressing the gastro-intestinal tract.

L'invention concerne une fraction de lait pouvant être obtenue par acidification de caséine micellaire et séparation de la caséine précipitée, cette fraction étant appelée protéine soluble dans l'acide issue de caséine micellaire. Il s'avère que la fraction de lait et en particulier certaines sous-fractions de celle-ci sont bioactives et favorisent la libération de GLP-1 in vitro. De ce fait, la protéine soluble dans l'acide issue de caséine micellaire peut être utile pour traiter et prévenir le diabète de type II et l'obésité et elle peut être ajoutée à des formules destinées à d'autres applications liées au tractus gastro-intestinal.

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