Human tumor necrosis factor delta and epsilon

Details Human tumor necrosis factor delta and epsilon Human tumor necrosis factor delta and epsilon

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/00 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) C07H 21/02 (2006.01) C07K 14/435 (2006.01) C07K 14/52 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12P 21/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/564 (2006.01)

Patent

CA 2413160

The invention relates to human TNF delta and TNF epsilon polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides, polypeptides, agonists and antagonists for applications, which relate, in part, to research, diagnostic and clinical arts.

L'invention concerne des polypeptides des facteurs tumoraux humains (facteur TNF) delta et epsilon, des polynucléotides codant ces polypeptides, des procédés de préparation de ces polypeptides, en particulier, par expression de ces polynucléotides, ainsi que des agonistes et antagonistes de ces polypeptides. Elle concerne, de plus, des procédés servant à utiliser ces polynucléotides, polypeptides, agonistes et antagonistes dans des applications partiellement relatives à la recherche, aux méthodes diagnostiques et aux méthodes cliniques.

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