Controlled-release pharmaceutical composition for the oral...

A - Human Necessities – 61 – K

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A61K 9/48 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2066751

2066751 9200730 PCTABS00010 A pharmaceutical composition for the controlled release of non steroidal anti-inflammatory drugs, which gives effective plasmatic levels of drug during 12-24 hours. Said controlled-release composition includes: a) 3 or 4 dosage units (cores) containing 1/3 or 1/4 respectively of the drug total dose, said single dosage units consisting in tablets which can disgregate and/or in tablets which cannot disgregate, including the active ingredient as well as hydrophilic polymeric materials which can gradually release the active ingredients; and b) hard gelatin capsules containing 3 or 4 release units.

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