Novel 4-phenyl substituted tetrahydroisoquinolines...

Details Novel 4-phenyl substituted tetrahydroisoquinolines... Novel 4-phenyl substituted tetrahydroisoquinolines...

C - Chemistry, Metallurgy

07

D

C07D 491/04 (2006.01) A61K 31/47 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01) C07D 307/00 (2006.01) C07D 333/00 (2006.01) C07D 471/04 (2006.01) C07D 493/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2415532

Compounds are provided that, by way of their selective neurotransmitter binding useful for the treatment of various neurological and psychological disorders, e.g., ADHD. Such compounds are 4-phenyl substituted tetrahydroisoquinolines having the Formula IA, IB, IIA, IIB, IIIA or IIIC as set forth herein.

L'invention concerne des composés qui, en raison de leur liaison sélective à des neurotransmetteurs, sont utiles pour le traitement de divers troubles neurologiques et psychologiques, notamment le trouble déficitaire de l'attention avec hyperactivité. Ces composés sont des tétrahydroisoquinoléines 4-phényle substituées représentées par la formule IA, IB, IIA, IIB, IIIA ou IIIC définie dans le descriptif.

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