Tablets comprising candesartan cilexetil

Details Tablets comprising candesartan cilexetil Tablets comprising candesartan cilexetil

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 31/4184 (2006.01) A61K 31/54 (2006.01) A61K 47/14 (2006.01) A61K 47/34 (2006.01) C07D 413/10 (2006.01)

Patent

CA 2654493

Composition in the form of a tablet, comprising candesartan cilexetil and optionally further active agents and usual adjuncts, wherein the surface of at least the active agent candesartan cilexetil in this composition is provided with a coating, made from a compound or a mixture of compounds selected from tri-(C1-C6) alkyl citrate, di-(C1- C6) alkyl phthalate, di-(C1-C6) alkyl sebacate and polydimethysiloxanes and methods for production thereof.

L'invention concerne une composition sous forme d'un comprimé, renfermant du candesartan cilexetil et, éventuellement, d'autres principes actifs, ainsi que des substances d'addition courantes, caractérisée en ce que dans ladite composition, la surface au moins du principe actif candesartan cilexetil est pourvue d'un enrobage constitué par un composé ou par un mélange de composés, sélectionnés à partir d'un trialkyl (C1-C6) citrate, d'un dialkyl (C1-C6) phtalate, d'un dialkyl (C1-C6) sébaçate et de polydiméthylsiloxanes. L'invention concerne en outre un procédé de fabrication de la composition précitée.

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