Compositions and methods of using rna interference for...

C - Chemistry – Metallurgy – 12 – N

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Details

IPC codes

C12N 15/82 (2006.01) C07K 14/435 (2006.01) C12N 15/11 (2006.01) A01H 5/00 (2006.01)

Type

Patent

Patent number

CA 2722095

Description

The present invention provides double stranded RNA compositions and transgenic plants capable of inhibiting ex-pression of essential genes in parasitic nematodes, and methods associated therewith. Specifically, the invention relates to the use of RNA interference to inhibit expression of a target essential nematode gene, which is a nematode innexin -like, pas- 1, tcp- 1, snurportin-1 like, pol delta S, prs-4, rtp-1 or rpn-5 gene, and relates to the generation of plants that have increased resistance to parasitic nematodes.

La présente invention porte sur des compositions d'ARN double brin et sur des plantes transgéniques capables d'inhiber l'expression de gènes essentiels dans des nématodes parasitaires, et sur des procédés associés à celles-ci. De façon spécifique, l'invention porte sur l'utilisation d'une interférence d'ARN pour inhiber l'expression d'un gène de nématode essentiel cible, qui est un gène de type innexine, pas-1, tcp-1, snurportine-1, pol delta S, prs-4, rtp-1 ou rpn-5 de nématode et porte sur la génération de plantes qui ont une résistance accrue envers les nématodes parasitaires.

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