N-hydroxyamide derivatives and use thereof

Details N-hydroxyamide derivatives and use thereof N-hydroxyamide derivatives and use thereof

C - Chemistry, Metallurgy

07

D

C07D 295/18 (2006.01) A61K 31/495 (2006.01) A61P 29/00 (2006.01) C07D 317/34 (2006.01)

Patent

CA 2592154

The present invention is related to N-hydroxyamide derivatives of Formula (I) and use thereof in particular for the treatment and/or prophylaxis of autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, cancer, respiratory diseases and fibrosis, including multiple sclerosis, arthritis, emphysema, chronic 5 obstructive pulmonary disease, liver and pulmonary fibrosis.

L'invention porte sur des dérives de la N-hydroxyamide de formule (I) et sur leurs utilisations en particulier pour le traitement et/ou la prophylaxie de troubles auto-immunes, de maladies inflammatoires, de maladies neurodégénératives, du cancer, de troubles respiratoires, et de fibroses dont la sclérose en plaques, l'arthrite l'emphysème, la bronchopneumopathie obstructive chronique, et les fibroses hépatiques et pulmonaires.

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