A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/14 (2006.01) A23L 1/30 (2006.01) A61P 3/02 (2006.01) A61P 7/02 (2006.01)
Patent
CA 2619145
Choline deficiency is a risk factor for the development of thrombosis in patients with intestinal failure that require total parenteral nutrition. There is provided a method of preventing thrombosis, preferably venous thrombosis, comprising administering to a patient receiving TPN a nutrient solution comprising choline. Also provided is a method of diagnosing a risk for thrombosis comprising taking a sample from a patient and detecting the level of plasma- free choline.
Un défaut en choline est un facteur de risque de développement d'une thrombose chez les patients atteints d'une déficience intestinale et qui nécessitent une nutrition parentérale totale. La présente invention décrit une méthode de prévention de thrombose, préférentiellement de thrombose veineuse, qui comprend l'administration à un patient soumis à NPT d'une solution de nutriments comprenant de la choline. La présente invention décrit également une méthode de diagnostic d'un risque de thrombose, qui comprend le prélèvement d'un échantillon chez un patient et la détection de la teneur en choline plasmatique libre.
Buchman Alan L.
Buchman Alan L.
Ridout & Maybee Llp
LandOfFree
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