Pharmaceutical compositions, kits and methods comprising...

Details Pharmaceutical compositions, kits and methods comprising... Pharmaceutical compositions, kits and methods comprising...

A - Human Necessities

61

K

A61K 31/40 (2006.01) A61K 31/565 (2006.01) A61K 31/567 (2006.01) A61K 31/57 (2006.01) A61P 5/30 (2006.01)

Patent

CA 2448235

The present invention relates to pharmaceutical compositions, kits and methods comprising combinations of (-)-cis-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)- phenyl]-5,6,7,8-tetrahydro-naphthalene-2-ol or nontoxic pharmacologically acceptable acid addition salts thereof and estrogens. The present invention also relates to pharmaceutical compositions, kits and methods comprising combinations of (-)-cis-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6, 7 ,8-tetrahydro-naphthalene-2-o1 or nontoxic pharmacologically acceptable acid addition salts thereof, estrogens and progestins.

La présente invention concerne des compositions pharmaceutiques, des nécessaires et des méthodes faisant intervenir des combinaisons de (-)-cis-6-phényl-5-[4-(2-pyrrolidin-1-yl-éthoxy)-phényl]-5,6,7,8-tetrahydro-naphtalène-2-ol ou de sels d'addition acides non toxiques pharmaceutiquement acceptables de cette substance et d'oestrogènes. La présente invention concerne également des compositions pharmaceutiques, des nécessaires et des méthodes faisant intervenir des combinaisons de (-)-cis-6-phényl-5-[4-(2-pyrrolidin-1-yl-éthoxy)-phényl]-5,6, 7,8-tetrahydro-naphtalène-2-ol ou de sels d'addition acides non toxiques pharmaceutiquement acceptables de cette substance, d'oestrogènes et de progestines.

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