Transmembrane protein differentially expressed in cancer

Details Transmembrane protein differentially expressed in cancer Transmembrane protein differentially expressed in cancer

C - Chemistry, Metallurgy

07

H

C07H 1/00 (2006.01) A01N 37/18 (2006.01) A01N 43/04 (2006.01) A01N 61/00 (2006.01) A61K 31/00 (2006.01) A61K 31/70 (2006.01) A61K 35/14 (2006.01) A61K 38/00 (2006.01) A61K 38/16 (2006.01) C07H 5/04 (2006.01) C07H 5/06 (2006.01) C07H 19/00 (2006.01) C07H 21/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 1/00 (2006.01) C07K 2/00 (2006.01) C07K 4/00 (2006.01) C07K 5/00 (2006.01) C07K 7/00 (2006.01) C07K 14/00 (2006.01) C07K 14/705 (2006.01) C07K 16/00 (2006.01) C07K 17/00 (2006.01) C07K 17/14 (200

Patent

CA 2458381

The invention provides a transmembrane protein, TMDC, that is differentially expressed in a colon or stomach cancer. It also provides for the use of the protein, a cDNA encoding the protein, and antibodies that specifically bind the protein in various methods to diagnose, stage, treat, or monitor the progression or treatment of a colon or stomach cancer.

L'invention concerne une protéine transmembranaire, TMDC, exprimée de manière différentielle dans un cancer du côlon ou de l'estomac. L'invention concerne également l'utilisation de la protéine, d'un ADNc codant la protéine et d'anticorps se liant de manière spécifique à la protéine dans plusieurs méthodes permettant de diagnostiquer, de traiter ou de surveiller la progression ou le traitement d'un cancer du côlon ou de l'estomac ou d'établir le stade de cette progression ou de ce traitement.

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