Phosphonic acid biaryl derivatives as inhibitors of protein...

Details Phosphonic acid biaryl derivatives as inhibitors of protein... Phosphonic acid biaryl derivatives as inhibitors of protein...

C - Chemistry, Metallurgy

07

F

C07F 9/38 (2006.01) A61K 31/66 (2006.01) C07F 9/553 (2006.01) C07F 9/6506 (2006.01) C07F 9/6518 (2006.01) C07F 9/6524 (2006.01) C07F 9/653 (2006.01) C07F 9/6539 (2006.01) C07F 9/6541 (2006.01) C07F 9/6558 (2006.01)

Patent

CA 2394834

The invention encompasses the novel class of compounds represented by formula (I), which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, including diabetes, obesity, and diabetes-related conditions.

La présente invention concerne une nouvelle classe de composés correspondant à la formule (I) qui sont des inhibiteurs de l'enzyme de PTP-1B. L'invention concerne également des compositions pharmaceutiques et de procédés de traitement et de prévention des maladies causées par la PTP-1B, y compris le diabète, l'obésité et des conditions pathologiques liées au diabète.

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