Derivatives of human bile-salt stimulated lipase, and...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/55 (2006.01) A23C 9/152 (2006.01) A61K 38/46 (2006.01) A61P 3/00 (2006.01) C12N 9/20 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2083396

The present invention relates to new DNA sequences, to new proteins coded for by such DNA sequences, and to the use as further described below of such proteins. The invention also encompasses vectors, such as plasmid constructs, comprising such DNA sequences, being capable of expressing the desired enzyme. The invention also includes host organisms transfected with such constructs e.g. bacteria yeast, mammalian cells, and transgenic animals. The invention also includes processes for the preparation of the novel products of the invention. The new proteins of the invention are related to an enzyme, known i.a. as human bile salt-stimulated lipase.

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