Sustained delivery formulations of octreotide compounds

Details Sustained delivery formulations of octreotide compounds Sustained delivery formulations of octreotide compounds

A - Human Necessities

61

K

A61K 9/14 (2006.01)

Patent

CA 2590696

The present invention relates to an octreotide sustained release delivery system for treatment of diseases relating to somatotropin and/or somatostatin. The sustained release delivery system of the invention includes a flowable composition containing an octreotide compound, and an implant containing the octreotide compound. The flowable composition may be injected into tissue whereupon it coagulates to become the solid or gel, monolithic implant. The flowable composition includes a biodegradable, thermoplastic polymer, an organic liquid and an octreotide compound.

L'invention porte sur un système à libération continue de traitement de maladies par des substances apparentées à la somatotropine et/ou la somatostatine. Ledit système consiste en une préparation fluide comprenant un composé d'octréotide et en un implant contenant ledit composé d'octréotide. La préparation fluide, qui peut s'injecter dans des tissus où elle se coagule pour former un implant monolithique solide ou un gel, comprend un agent biodégradable, un polymère thermoplastique, un liquide organique et un composé d'octréotide.

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