Oral formulations containing mucopolysaccharide for small...

Details Oral formulations containing mucopolysaccharide for small... Oral formulations containing mucopolysaccharide for small...

A - Human Necessities

61

K

A61K 31/726 (2006.01) A61K 9/20 (2006.01) A61K 31/727 (2006.01) A61K 31/728 (2006.01) A61K 31/737 (2006.01) A61K 47/14 (2006.01) A61K 47/28 (2006.01) A61K 47/44 (2006.01) A61P 7/02 (2006.01) A61P 7/04 (2006.01) A61K 9/48 (2006.01) A61K 47/12 (2006.01) A61K 47/18 (2006.01)

Patent

CA 2438707

An oral administrable enteric formulation of mucopolysaccharide is provided by using an absorption enhancer for mucopolysaccharide comprising of fatty acid having 6 to 14 carbon atoms or salt, ester and amide derivative thereof; steroid carboxylic acid, or salt, ester and amide derivative thereof; and aliphatic poly-basic acid, or salt, ester and amide derivative thereof; or mixture thereof. Said mucopolysaccharide has been only administered by the injection formulations, and the effective blood concentration of said mucopolysaccharide has not been obtained by oral administration.

On produit une préparation entérique à administrer par voie orale, contenant un mucopolysaccharide, en utilisant un agent augmentant l'absorption pour le mucopolysaccharide, comprenant un acide gras possédant 6 à 14 atomes de carbone ou un sel, un ester ou un dérivé amide de celui-ci ; de l'acide carboxylique stéroïde, ou un sel, un ester ou un dérivé amide de celui-ci ; et un acide polybasique aliphatique, ou un sel, un ester ou un dérivé amide de celui-ci ; ou des mélanges de ceux-ci. Ledit mucopolysaccharide a seulement été administré dans des préparations à injecter et la concentration effective dans le sang de mucopolysaccharide n'a pas été obtenue par administration orale.

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