Tr3-specific binding agents and methods for their use

Details Tr3-specific binding agents and methods for their use Tr3-specific binding agents and methods for their use

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07K 16/28 (2006.01) C12N 5/20 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2391530

Biologically active TR3-specific binding agents and methods for their use are disclosed. The biologically active TR3-specific binding agents are useful for inhibiting the proliferation of cells expressing TR3. These biologically active agents are particularly useful for treating T-cell mediated diseases such as graft-versus-host disease, organ rejection, tumor growth, autoimmunity, and inflammation.

L'invention concerne des agents de liaison biologiquement actifs spécifiques à TR3. Ces agents sont utiles pour inhiber la prolifération de cellules exprimant TR3. Ces agents biologiquement actifs sont particulièrement utiles pour traiter les maladies induites par les lymphocytes T, telles la réaction de greffe contre hôte, le rejet d'organes, la croissance tumorale, l'auto-immunité et l'inflammation.

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