A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/52 (2006.01) A61P 17/02 (2006.01) C07D 473/32 (2006.01)
Patent
CA 2607589
Pharmaceutical compositions comprising tricyclic 3,4-propinoperhydropurines and uses thereof for treating wounds, anal fissure, achalasia, disorders of the upper and lower esophageal sphincter, gastroparesis, hypertrophic pyloric stenosis, hemorrhoids, proctalgia fugax, irritable bowel syndrome, muscular spasms, vasospastic disorders, disorders involving uterine, or bladder spasm, sphincter of Oddi dysfunction, and short-segment Hirschprung's are provided. Also provided are methods of treating wounds and muscle disorders by administering the composition of the invention to a muscle or in the vicinity of a muscle either topically or by injection.
L'invention porte sur des compositions pharmaceutiques comprenant des 3,4-propinoperhydropurines tricycliques et sur leurs utilisations dans le traitement des plaies, d'une fissure anale, de l'achalasie, des troubles du sphincter oesophagien supérieur et inférieur, de la gastroparésie, de la sténose pylorique hypertrophique, des hémorroïdes, de la proctalgie fugace, du syndrome du côlon irritable, des spasmes musculaires, des troubles vasospastiques, des troubles impliquant des spasmes utérins ou de la vessie, du dysfonctionnement du sphincter d'Oddi et de la forme courte de la maladie de Hirschprung. L'invention porte également sur des méthodes de traitement des plaies et des maladies musculaires qui consistent à administrer la composition de l'invention dans un muscle ou à proximité d'un muscle soit par application locale, soit par injection.
Mbm Intellectual Property Law Llp
Phytotox Limited
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