Pharmaceutical formulations of antineoplastic agents, in...

Details Pharmaceutical formulations of antineoplastic agents, in... Pharmaceutical formulations of antineoplastic agents, in...

A - Human Necessities

61

K

A61K 9/08 (2006.01) A61K 31/4188 (2006.01) A61K 47/16 (2006.01) A61K 47/18 (2006.01) A61P 35/00 (2006.01) A61K 47/10 (2006.01) A61K 47/30 (2006.01)

Patent

CA 2662899

In its several embodiments, this invention discloses a pharmaceutical formulation comprising at least one antineoplastic agent or a pharmaceutically acceptable salt thereof, and at least one dissolution enhancing agent sufficient to substantially dissolve said at least one antineoplastic agent in at least one aqueous diluent, wherein said dissolution enhancing agent is urea, L- histidine, L-threonine, L-asparagine, L-serine, L-glutamine or mixtures thereof; a lyophilized powder comprising said pharmaceutical formulation, and articles of manufacture thereof.

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