Multi-through hole testing plate for high throughput screening

G - Physics – 01 – N

Patent

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Details

G01N 35/00 (2006.01) B01L 3/00 (2006.01) C40B 20/00 (2006.01) C40B 30/00 (2006.01) C40B 60/12 (2006.01) G01N 35/10 (2006.01)

Patent

CA 2367912

A method for holding samples for analysis and an apparatus thereof includes a testing plate with a pair of opposing surfaces and a plurality of holes. Each of the holes extends from one of the opposing surfaces to the other one of the opposing surfaces. The holes are arranged in groups, where each group has at least two rows and two columns of holes. The groups are arranged in sets, where each set has at least two rows and two columns of groups. To analyze samples, at least one of the opposing surfaces of the testing plate is immersed in a solution to be analyzed. A portion of the solution enters openings for each of the holes in the immersed opposing surface. Once the holes are filled with solution, the testing plate is removed and is held above a supporting surface. Surface tension holds the solution in each of the holes. The solution in one or more of the holes is then analyzed and the solution in one of these holes is identified for further study. The location of the identified solution is marked based upon its location within a particular set and group of holes.

La présente invention concerne, d'une part un procédé de tenue des échantillons destinés à une analyse, et d'autre part un appareil à cet effet. On a recours à une plaque d'essais comportant une paire de surfaces opposées et une pluralité de trous. Chacun des trous traverse la plaque de part en part. Les trous sont disposés par groupes à raison d'au moins deux rangées et deux colonnes de trous par groupe, les groupes étant disposés par ensembles à raison d'au moins deux rangées et deux colonnes de groupes par ensemble. Pour analyser les échantillons, on plonge l'une au moins des surfaces opposées de la plaque d'essais dans une solution à analyser. Une partie de la solution pénètre par les orifices de chacun des trous dans la surface opposée immergée. Une fois que les trous sont remplis de solution, on retire la plaque d'essais et on la pose au-dessus d'une surface support. La tension superficielle maintient la solution dans chacun des trous. La solution de l'un au moins des trous est alors soumise à analyse, à la suite de quoi on identifie la solution de l'un de ces trous pour la suite de l'étude. L'emplacement de la solution identifié est repéré en fonction de sa position dans des ensembles et des groupes définis.

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