The combination of growth hormone and insulin-like growth...

Details The combination of growth hormone and insulin-like growth... The combination of growth hormone and insulin-like growth...

A - Human Necessities

61

K

A61K 38/30 (2006.01)

Patent

CA 2185998

Methods of enhancing myocardial contractility and cardiac performance in a mammal with congestive heart failure are disclosed. In a first method a mammal with congestive heart failure is treated by administering to the mammal an effective amount of a combination of growth hormone (GH) and insulin-like growth factor (IGF-I). A second method comprises administering to the mammal an effective amount of a combination of GH and IGF-I in the presence of an ACE inhibitor. This method results in enhancement of myocardial contractility and cardiac performance above the level achieved with ACE inhibition alone. Preferably the mammal is a human.

Procédé d'amélioration de la contractilité du myocarde et de la performance cardiaque chez un mammifère atteint d'insuffisance cardiaque. Dans un premier procédé, on traite un mammifère atteint d'insuffisance cardiaque en lui administrant une quantité efficace d'une combinaison d'hormone de croissance (GH) et d'hormone de croissance de type I proche de l'insuline (IGF-I). Un second procédé consiste à administrer au mammifère une quantité efficace d'une combinaison de GH et d'IGF-I en présence d'un inhibiteur d'enzyme de conversion de l'angiotensine (ACE). Ledit procédé entraîne une amélioration de la contractilité du myocarde et de la performance cardiaque supérieure aux résultats atteints avec la seule inhibition de l'ACE. De préférence, ledit mammifère est un être humain.

Affiliated with

Also associated with

Rating

The combination of growth hormone and insulin-like growth... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with The combination of growth hormone and insulin-like growth..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and The combination of growth hormone and insulin-like growth... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1774649