Method for the synthesis of huperzine a and analogs thereof...

C - Chemistry – Metallurgy – 07 – D

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C07D 221/22 (2006.01) A61K 31/435 (2006.01) C07D 215/48 (2006.01)

Patent

CA 2047744

The present invention relates to a method for the synthesis of certain bridged fused ring pyridines. Such bridged fused ring pyridines can be converted to huperzine A of the formula: (see formula I) and analogs of huperzine A. The present invention also covers such bridged fused ring pyridines, compounds utilized for the preparation of the bridged fused ring pyridines and analogs of huperzine A.

La présente invention concerne un procédé de synthèse de certaines pyridines cycliques pontées fusionnées. De telles pyridines cycliques pontées fusionnées peuvent être converties en huperzine A et en analogues de l'huperzine A. La présente invention concerne également de telles pyridines cycliques pontées fusionnées, des composés utilisés pour la préparation des pyridines cycliques pontées fusionnées et des analogues de l'huperzine A.

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