Oxalic acid derivatives

Details Oxalic acid derivatives Oxalic acid derivatives

C - Chemistry, Metallurgy

07

C

C07C 311/46 (2006.01) A61K 31/167 (2006.01) A61K 31/18 (2006.01) A61P 9/10 (2006.01) A61P 29/00 (2006.01) C07C 257/18 (2006.01) C07C 317/32 (2006.01) C07D 207/26 (2006.01) C07D 207/263 (2006.01) C07D 211/76 (2006.01) C07D 223/10 (2006.01) C07D 271/06 (2006.01)

Patent

CA 2445538

Novel compounds of the formula (I) in which R1, R2, R3, R4, X and Z are as defined in Patent Claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic disorders and for the treatment of tumours.

l'invention porte sur de nouveaux composés représentés par la formule (I) dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, X et Z tels que définis dans les revendications 1 de la présente invention, sont des inhibiteurs du facteur de coagulation Xa et peuvent être utilisés dans la prophylaxie et/ou la thérapie des troubles thromboemboliques et dans le traitement de tumeurs.

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