Method for screening compounds using nematode worms

Details Method for screening compounds using nematode worms Method for screening compounds using nematode worms

C - Chemistry, Metallurgy

12

Q

C12Q 1/02 (2006.01) A01K 67/033 (2006.01) C12N 1/20 (2006.01) C12Q 1/18 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2369734

The invention provides improved methods of screening compounds for potential pharmacological activity using nematode worms, principally but not exclusively.C. elegans. Specifically, the invention relates to methods in which the compound under test is added directly to a nematode food source organism and therefore taken up by the nematodes during feeding.

Cette invention concerne des procédés améliorés de criblage de composés présentant une activité pharmacologique potentielle au moyen de nématodes, principalement, mais pas exclusivement de C. elegans. L'invention concerne en particulier des procédés selon lesquels le composé testé est ajouté directement à un organisme dont se nourrit directement un nématode et absorbé par ce dernier.

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