Tek antagonists

Details Tek antagonists Tek antagonists

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 14/71 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2374851

The present invention provides Tek antagonists and methods of inhibiting angiogenesis in a mammal by administering Tek antagonists. The methods are particularly useful in treating diseases or conditions mediated by angiogenesis, such as solid tumors and diseases or conditions characterized by ocular neovascularization.

La présente invention concerne des antagonistes Tek et des procédés destinés à inhiber l'angiogenèse chez un mammifère en lui administrant des antagonistes Tek. Ces procédés sont notamment utilisés dans le traitement de maladies ou d'états pathologiques en rapport avec l'angiogenèse, tels que les tumeurs solides et les maladies ou les états pathologiques caractérisés par une néovascularisation oculaire.

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