Compositions and methods for treating leukemia

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/127 (2006.01) A61K 31/475 (2006.01) A61K 31/573 (2006.01)

Patent

CA 2576222

The present invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of leukemias, including acute lymphoblastic leukemia (ALL). These methods involve the administration of liposome-encapsulated vinca alkaloids, e.g., vincristine, in combination with dexamethasone to a mammal with a leukemia.

L'invention concerne des procédés pour traiter des néoplasmes chez un mammifère. Cette invention concerne en particulier des procédés pour traiter différents types de leucémie, y compris la leucémie lymphoblastique aiguë (ALL). Lesdits procédés consistent à administrer des alcaloïdes de Vinca encapsulés dans des liposomes, par exemple de la vincristine, en association avec de la dexaméthasone, à un mammifère présentant une leucémie.

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