Small molecule correctors of deltaf508 cftr trafficking

Details Small molecule correctors of deltaf508 cftr trafficking Small molecule correctors of deltaf508 cftr trafficking

C - Chemistry, Metallurgy

07

D

C07D 487/14 (2006.01) A61K 31/55 (2006.01) A61P 11/00 (2006.01) A61P 11/12 (2006.01)

Patent

CA 2728366

This invention provides compounds of Formula I. The compounds are correctors of .DELTA.F508 CFTR trafficking. Also provided are uses of compounds of Formula I for treatment, as well as methods of treatment, of cystic fibrosis.

L'invention concerne des composés représentés par la formule I. Ces composés sont des correcteurs du transport de ?F508 CFTR. L'invention concerne également des utilisations des composés de formule I pour le traitement de la mucoviscidose, ainsi que des méthodes de traitement de la mucoviscidose.

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