Ionic polymers comprising an amino or ammonium group as...

A - Human Necessities – 61 – K

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167/206, 167/279

A61K 31/785 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2259344

A method for treating a microbial infection in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising an amino group or an ammonium group attached to the polymer backbone via an aliphatic spacer group. The polymer can be a homopolymer or a copolymer. In one embodiment, the polymer is a copolymer comprising a monomer having a pendant ammonium group and a hydrophobic monomer.

Procédé de traitement d'une infection microbienne chez un mammifère, tel qu'un être humain, consistant à traiter celui-ci avec une quantité thérapeutiquement efficace d'un polymère comprenant un groupe amino ou un groupe ammonium fixé à la structure du polymère via un groupe d'espacement aliphatique. Le polymère peut être un homopolymère ou un copolymère. Dans un mode de réalisation, le polymère est un copolymère comprenant un monomère ayant un groupe ammonium pendant et un monomère hydrophobe.

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